Site Rotation Example

Since Tesamorelin requires a larger volume (usually 40 units for a 2mg dose), injecting into the same spot every night is a fast track to "lump city." The 10mg vials are great, but the daily volume means you have to be tactical with your skin real estate.

Here is how to manage the rotation and minimize that "spicy" post-injection sting:

1. The "Clockwork" Rotation
Imagine a clock face around your belly button (staying at least 2 inches away from the navel itself).
• Monday: 12 o’clock
• Tuesday: 3 o’clock
• Wednesday: 6 o’clock
• Thursday: 9 o’clock
• Friday: Switch to the "outer ring" (love handles) or upper thigh.

2. Manage the "Tesamorelin Itch"
Tesamorelin is notorious for causing a localized histamine reaction (redness, itching, or a small welt). To fix this:

• Temperature: Let the syringe sit at room temperature for 3–5 minutes before injecting. Cold peptide often stings more.

• The Wipe: After cleaning the site with alcohol, let it dry completely. If you "push" wet alcohol into the skin with the needle, it burns.

• Post-Shot: Do not rub the site immediately after. If it itches, you can use a cold compress or a tiny dab of Benadryl cream after the injection site has closed.

3. Injection Technique for Higher Volume

• Angle: Go in at a 90-degree angle if you have enough body fat, or a 45-degree angle if you are leaner, to ensure you stay in the subcutaneous layer and don't hit muscle.

• Speed: Inject the 40 units slowly. Pushing a large volume of liquid in 1 second causes tissue trauma; aim for a steady 3–5 second "slow push."

4. Record Keeping

Since you’re doing 5 days on and 2 days off, it’s easy to lose track.

• Tip: Mark your "Off" days on your calendar (e.g., Saturday/Sunday). This gives your pituitary gland a "breather" and helps prevent the site irritation from becoming chronic.

Rotation "Pro-Tips" for your Website
If you are putting this on your site or in a guide, you should pair the image with these three rules to prevent "Lipohypertrophy" (the hard lumps that can form from overusing one spot):

The 1-Inch Rule: Even within the same quadrant, never inject into the exact same spot twice in a row. Move at least 1 inch (the width of two fingers) away from your last poke.

The "Pinch" Check: Always pinch the skin to ensure you’re hitting the fatty subcutaneous layer and not the muscle. If it feels "tight" or "hard," move to a softer area.

The "Mirror" Warning: Remember that when you look in the mirror, your "Right" is the image's "Left." Most people find it easier to label their quadrants as "My Right" and "My Left" to avoid confusion.