Melanotan 2

Melanotan 2 (MT2) is a potent synthetic analog of alpha-melanocyte-stimulating hormone ($\alpha$-MSH). While it is more powerful than Melanotan 1, it is less selective, meaning it often produces more pronounced side effects (specifically appetite suppression and increased libido) alongside skin pigmentation.
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1. Reconstitution & Dosage

Melanotan 2 typically comes in 10mg vials. Because of its extreme potency, many researchers prefer to use more water for reconstitution to make measuring small doses easier.

• Reconstitution: Add 2ml of Bacteriostatic Water to a 10mg vial.
• The Concentration: This creates 5mg (5,000mcg) per 1ml.
• Syringe Measurement (U-100 Insulin Syringe):
o 2 units (0.02ml) = 100mcg (Common assessment dose)
o 5 units (0.05ml) = 250mcg (Standard research dose)
o 10 units (0.10ml) = 500mcg (Strong dose—often causes nausea)

Common Research Dosages:
• Day 1–3 (Acclimation): 100mcg per day to check for severe nausea.
• Standard Dose: 250mcg per day.
• Aggressive Dose: 500mcg per day (Rarely needed for most skin types).
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2. The Cycle (Loading & Maintenance)
MT2 is highly cumulative. Once the melanin is stimulated, it remains in the skin for a significant amount of time.

Phase Duration Frequency
Loading Phase 7–14 Days (Until base tan is achieved) Once Daily
Maintenance Phase Ongoing 1–2 Times Per Week

The "UV Trigger": MT2 provides a baseline tan, but for the "golden" look most researchers seek, short bursts of UV exposure (10 minutes) every 3 days are used to lock in the color.
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3. Administration & Storage

• Injection Type: Subcutaneous (SubQ) in the abdominal fat.

• Timing: Nightly, right before bed. This is the "Golden Rule" for MT2 because the nausea typically peaks 30–60 minutes after injection. By sleeping through it, the researcher avoids discomfort.

• Storage: Once reconstituted, the vial must be refrigerated.

• Fragility: Do not shake; the peptide bonds are delicate.
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4. Potential Side Effects (The "MT2 Profile")
MT2 is famous for several systemic effects that go beyond tanning:
• Nausea & Stomach Cramps: Very common during the loading phase.
• Appetite Suppression: Many researchers report a significant decrease in hunger.
• Increased Libido: Spontaneous arousal can occur, often lasting several hours post-injection.
• Hyperpigmentation: Darkening of existing moles or the appearance of new "freckles" (melanocytes clustering). These usually fade after the cycle ends.
• Yawning/Stretching: An odd but common side effect where the user feels a frequent need to yawn and stretch.
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5. Summary Checklist for a 10mg Vial
• Reconstitute with: 2ml Bacteriostatic Water.
• Standard Dose (250mcg): Pull to the 5 unit mark on a 1ml syringe.
• Vial Longevity: At 250mcg per day, one vial lasts 40 days.