Ipamorelin

Ipamorelin is widely considered the "gold standard" of Growth Hormone Secretagogues because it is highly selective. Unlike older peptides (like GHRP-2 or GHRP-6), Ipamorelin does not significantly increase hunger (ghrelin) or stress hormones like cortisol and prolactin.

It is often used for lean muscle gain, fat loss, and improved sleep quality.
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1. Reconstitution & Dosage
Ipamorelin usually comes in 2mg or 5mg vials. It is almost always dosed in micrograms (mcg).
• Reconstitution: Add 2ml of Bacteriostatic Water to a 5mg vial.
• The Concentration: This creates 2.5mg (2,500mcg) per 1ml.
• Syringe Measurement: On a standard U-100 insulin syringe:
o 4 units (0.04ml) = 100mcg (Standard starting dose)
o 8 units (0.08ml) = 200mcg (Standard research dose)
o 12 units (0.12ml) = 300mcg (High-end dose)

Common Research Dosages:
• Anti-Aging/Sleep: 100mcg – 200mcg once nightly.
• Body Composition/Recovery: 200mcg – 300mcg split into two doses (Morning and Night).
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2. The Cycle (Duration & Timing)
Ipamorelin works best when it mimics the body's natural growth hormone pulses.

Parameter Recommendation
Cycle Length 12–16 Weeks (Longer cycles are common for GH peptides)
Weekly Schedule 5 Days ON / 2 Days OFF

Timing Nightly, right before bed, at least 2 hours after your last meal.

The "Golden Rule" of Ipamorelin: You must be in a fasted state. If insulin is present (from eating carbs or fats recently), it will blunt the growth hormone pulse, making the injection much less effective.
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3. The "CJC-1295" Synergy
In the research world, you will rarely see Ipamorelin used alone. It is almost always paired with CJC-1295 (No DAC).
• Ipamorelin provides the pulse (the height of the wave).
• CJC-1295 provides the duration (the length of the wave).
• Together, they are significantly more powerful than either one alone.
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4. Storage & Stability
• Refrigeration: Must be kept in the fridge after mixing.
• Fragility: Like Tesamorelin, it is a delicate peptide. Do not shake.
• Longevity: Best used within 21–28 days of reconstitution.
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5. Potential Side Effects
• Head Rush: A very brief "head rush" or feeling of warmth immediately after injection.
• Improved Sleep: This is a "side effect" most users love—deeper REM sleep and more vivid dreams.
• Water Retention: At higher doses (300mcg+), you may notice slight swelling in the fingers or ankles.
• Carpal Tunnel Symptoms: Very rare, but high GH levels can cause temporary tingling in the hands.
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Quick Checklist for your 5mg Vial:
• To hit a 200mcg dose: Pull to the 8 unit mark on your syringe (assuming 2ml of water).
One vial will last you 25 days if injecting once daily.