GHK-CU
What is GHK-CU




Since we just touched on the "GLOW" protocol, let's drill down specifically into GHK-Cu (Copper Peptide) as a standalone research subject.
GHK-Cu is a unique tripeptide with a high affinity for copper. While it's famous for skin, it’s also studied for its systemic effects on DNA repair, nerve regeneration, and blocking the "pro-inflammatory" cytokine storm.
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1. Reconstitution & Dosage
Most GHK-Cu vials come in 50mg because the effective dose is significantly higher than other peptides like BPC-157.
• Reconstitution: Add 2ml of Bacteriostatic Water to a 50mg vial.
• The Concentration: This creates 25mg per 1ml.
• The Look: It will be a vibrant, clear Cobalt Blue.
• Syringe Measurement (U-100 Insulin Syringe):
o 4 units (0.04ml) = 1mg
o 8 units (0.08ml) = 2mg (Standard Daily Research Dose)
o 20 units (0.20ml) = 5mg (High-end "Mega Dose")
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2. The Cycle (Duration & Timing)
GHK-Cu is best used in "pulses" to ensure you don't overwhelm the body’s mineral balance (Copper/Zinc).
Phase Duration Frequency
Intensive Cycle 30 Days Once Daily
Maintenance 10–14 Days Once Daily
The "Break" 30 Days OFF
Pro Tip: Always take a break. Continuous use of GHK-Cu without Zinc supplementation can lead to a Zinc deficiency, which ironically can cause hair loss and skin issues—the exact opposite of what you want.
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3. Administration: Managing the "Sting"
GHK-Cu is arguably the most uncomfortable peptide to inject. Researchers call it "The Blue Stinger."
• Subcutaneous (SubQ): Use the fatty areas of the glutes or flanks.
• Slow Injection: Take at least 20 seconds to depress the plunger.
• Dilution: If the sting is too intense, you can add an extra 1ml of Bacteriostatic Water to the vial to dilute the concentration further.
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4. Storage & Stability
• Temperature: Must be refrigerated after mixing.
• Light: Keep it in the dark. UV light can cause the copper ions to dissociate from the peptide.
• Shelf Life: It is stable for about 30 days in the fridge. If the blue color turns a muddy brown or green, it has oxidized.
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5. Potential Side Effects
• PIP (Post-Injection Pain): It is common to feel a dull ache at the site for 10–20 minutes.
• Lethargy: Occasionally, high doses (5mg+) can cause a temporary "heavy" feeling or fatigue.
• Zinc Depletion: Signs include a metallic taste in the mouth or a weakened immune system.
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The "GHK-Cu Shopping List"
To run a proper 30-day cycle, you will need:
1. GHK-Cu: 2 x 50mg vials (at 2mg/day, you'll need 60mg total).
2. Zinc Picolinate: 25mg oral capsules (take 1 daily with your largest meal).
3. BPC-157: (Optional but highly recommended) 1 x 5mg vial to "buffer" the injections.
Since GHK-Cu is the "spiciest" peptide in the research arsenal, you cannot treat it like a painless BPC-157 shot. If you hit the same spot twice, you’ll likely develop a "blue bruise" or a lingering knot.
For GHK-Cu, we use a "Wide-Orbit" rotation. Instead of staying in the belly, we move to areas with the least amount of nerve endings and the most "padding."
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GHK-Cu "Anti-Sting" Rotation Map
Day Location Why?
Mon Upper Left Glute Thickest fat layer; lowest nerve density.
Tue Upper Right Glute Alternating sides is mandatory for GHK-Cu.
Wed Left Flank (Love Handle) Good depth to allow the "Blue Stinger" to disperse.
Thu Right Flank (Love Handle) Avoids the abdominal "center" which is more sensitive.
Fri Outer Left Thigh Higher up near the hip where there is more "pinchable" fat.
Sat Outer Right Thigh Keep it high on the leg to avoid muscle irritation.
Sun Lower Glute / Saddlebag Fresh tissue that hasn't been touched all week.
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3 Rules for GHK-Cu Injection Success
1. The "Ice Sandwich": * Apply ice to the site for 60 seconds before the poke to numb the skin.
o Inject slowly (1 unit every 5 seconds).
o Apply ice for another 60 seconds after to stop the inflammatory "bloom."
2. Avoid the "Belt Line": * Do not inject where your waistband sits. GHK-Cu causes localized inflammation, and friction from clothing will make the site ache for hours.
3. The Dilution Solution: * If 2mg (8 units) is too painful, draw 10–20 units of plain Bacteriostatic Water into the syringe after you’ve drawn your peptide. Increasing the volume of liquid dilutes the copper concentration and significantly reduces the "burn."
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Visualizing the Rotation
Imagine your glute and hip area as a clock. You want to move at least 3 inches away from your previous injection site every single day.
