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5-Amino-1mq

What is 5-Amino-1mq?

5-Amino-1mq

5-amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule that acts as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). It is not a hormone and is being researched and used experimentally (off-label) for its potential role in metabolism, fat loss, and anti-aging by helping preserve levels of the vital coenzyme NAD+.

Key Information
Mechanism of Action: 5-amino-1MQ works by blocking the NNMT enzyme, which is often elevated in individuals with obesity and metabolic dysfunction and consumes a significant amount of NAD+. By inhibiting NNMT, it helps increase and preserve intracellular NAD+ levels, which in turn activates sirtuin-1 (SIRT1), the "longevity gene," and improves mitochondrial function.

Potential Benefits:
--Enhanced fat metabolism and targeted fat loss (especially visceral fat).
--Preservation of lean muscle mass during weight loss.
--Improved insulin sensitivity and blood sugar control.
--Increased energy levels, endurance, and mental clarity.
--Support for cellular repair and healthy aging processes.

Regulatory Status: 5-amino-1MQ is a research compound and is not approved by the FDA for human use. Its safety, proper dosing, and long-term side effects have not been established through large-scale human clinical trials. It is typically only available for human use through compounding pharmacies under the supervision of a qualified healthcare provider.

Administration: It is typically administered orally in capsule form, although subcutaneous injections are also an option in clinical settings.

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